Understanding Lynch syndrome: implications for nursing

摘要: Colorectal cancer (CRC) is the second-leading cause of cancer-related death in United States. Approximately 10% CRC hereditary, and hereditary nonpolyposis (HNPCC), or Lynch syndrome I, most common form. I characterized by onset at an early age, poor differentiation, predominance proximal tumors, excess synchronous metachronous tumors. In II, patients exhibit features also have extracolonic cancers. inherited autosomal dominant disorder caused a germline mutation one several genes responsible for DNA mismatched repair. Amsterdam criteria, II Bethesda guidelines are international diagnostic criteria syndrome. Nursing care with includes identifying who would benefit from genetic counseling, providing education, assessing meeting patient psychosocial needs.