Thin-layer isoelectric focusing for haemoglobin screening and its application to haemoglobin Malmö

作者: J.O. Jeppsson , Stig Berglund

DOI: 10.1016/0009-8981(72)90263-X

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摘要: Abstract A thin-layer technique for isoelectric focusing of proteins in polyacrylamide gel was developed and applied to various haemoglobins. Small differences charge not detectable by conventional electrophoretic techniques were revealed. Thus Hb Malmo ( α 2 β 97 His → Gln ) could be separated from Hb-A, Hb-F I II . The method may preferably replace clinical work.

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