Mass fragmentographic analysis of homovanillic acid and its homoiso analogue in cerebrospinal fluid using the α-dideutero acid as internal standard
作者： Claes -G�ran Fri , Frits -Axel Wiesel , G�ran Sedvall
DOI: 10.1007/BF00429220
关键词:
摘要: The preparation and use of HVA-d2 for the mass fragmentographic determination HVA levels in CSF was described. Following extraction synthesis methyl ester heptafluorobutyryl derivatives samples were injected into a combined gas chromatograph-mass spectrometer connected to multiple ion detector. two fragments set focus molecular ions authentic respectively. experimental error less than 4%. recovery small amounts added satisfactory. Multiple using sets gave similar results demonstrating high specificity reproducibility method used.
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