THE 4-O-METHYL METABOLITES OF CATECHOLAMINES IN MAN: CHROMATOGRAPHIC IDENTIFICATION OF 3-HYDROXY,4-METHOXYPHENYLACETIC ACID (HOMO-ISO-VANILLIC ACID) IN CEREBROSPINAL FLUID
作者： P. Mathieu , L. Revol , P. Trouillas
DOI: 10.1111/J.1471-4159.1972.TB01255.X
关键词:
摘要: — The isomeric phenolic acids, homovanillic acid (4-hydroxy,3-methoxyphenylacetic acid) and homo-iso-vanillic (3-hydroxy,4-methoxyphenylacetic acid), were separated identified by means of paper chromatography their azo-derivatives with diazotized para-nitroaniline. Using this chromatographic procedure, homo-iso-vaniliic was in several samples human cerebrospinal fluid, an observation which suggests that dopamine may be partly metabolized brain, the production 4-methoxy derivatives.
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