Transient appearance of tyrosine hydroxylase-immunoreactive non-catecholaminergic neurons in the medial geniculate nucleus of postnatal mice

作者: Ikuko Nagatsu , Terumi Takeuchi , Masao Sakai , Nobuyuki Karasawa , Yoko Yamawaki

DOI: 10.1016/0304-3940(96)12753-1

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摘要: Tyrosine hydroxylase-immunoreactive (TH-ir) cells were found to appear transiently in the medial geniculate nuclear region of mice at postnatal day 7 (P7) by use an avidin-biotin peroxidase complex (ABC) method for first time. The numbers TH-ir reached maximum between P14 and P21 decreased until P29. These GTP cyclohydrolase I-negative, aromatic L-amino acid decarboxylase-negative, dopamine-negative. Thus, they do not belong catecholaminergic neuron system, because lack dopamine production. results suggest that TH has some new functions besides catecholamine biosynthesis.

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