Where have all the American celiacs gone

摘要: Celiac disease is a common cause of malabsorption in western countries, with significant geographic variation incidence. Recent epidemiological studies using serology tests, however, suggest that the more than previously realized and homogeneously distributed Europe. These have also demonstrated clinical presentation may greatly vary even between neighboring countries. remains rare diagnosis United States. Whether underdiagnosed or truly to be established. We conducted preliminary studies, both on pediatric patients adult blood donors, seem prevalence positive screening tests for celiac USA equivalent reported similar data dimensions American iceberg those European one. The visible tip iceberg, appears much smaller, since most it still submerged. reasons these divergences remain unknown only partially related limited attention by scientific community. Large, multicenter serological are needed define true