Risk of New-Onset Dyslipidemia After Laparoscopic Adrenalectomy in Patients with Primary Aldosteronism

摘要: Many patients with primary aldosteronism (PA) show a significant decline in kidney function after adrenalectomy. Thus, PA who undergo surgery are at greater risk of both postoperative renal damage and new-onset metabolic events associated insufficiency. The aim this study was to explore changes serum lipid levels identify factors dyslipidemia patients. records 57 Japanese underwent unilateral laparoscopic adrenalectomy for were retrospectively surveyed. Clinical biochemical data evaluated baseline 12 months surgery. Preoperative estimated glomerular filtration (eGFR) profile, including triglycerides, high-density lipoprotein (HDL)-cholesterol low-density (LDL)-cholesterol levels, compared. Furthermore, uni- multivariate analyses performed determine the predictors dyslipidemia. A decrease eGFR deterioration identified postoperatively most Of 39 without pre-existing dyslipidemia, 18 developed postoperatively. Multivariate analysis preoperative lower higher body mass index as independent On univariate analyses, additional included older age, male sex, LDL-cholesterol, LDL/HDL ratio. had or progressive Clinicians should pay attention not only follow-up impairment but also total management insufficiency