Recurrence of early gastric cancer : follow-up of 1475 patients and review of the Japanese literature

摘要: Background. The outcome of surgical treatment for early gastric cancer (EGC) generally is considered to be satisfactory. Although a small percentage patients experience disease recurrence, the absolute number such instances too assessment risk factors. Methods. authors investigated follow-up records 1475 with EGC treated at National Cancer Center, Tokyo, special reference recurrence. In addition, 20 Japanese reports on this subject were reviewed. Results. Excluding operative deaths and noncurative operations, (1.4%) died recurrent disease. death rate associated other causes (6.6%), including malignant diseases, sur-passed that Late recurrence (after 5 years) was seen in seven patients. By combining data reported articles literature, estimated least 1.9%, exclusive cancers arising stump. incidence significantly higher submucosal (3.6%), node-positive (10.7%), histologically differentiated carcinomas (2.3%) than mucosal, node-negative, undifferentiated groups, respectively. Analysis 123 disease, details which had been reported, revealed hematogenous metastasis most common mode mean survival period 40 months, 23% more years after surgery. Conclusion. It rare recur, even tumors comparatively high Long-term positive nodes spread might facilitate detection