Interferons alpha and gamma induce p53-dependent and p53-independent apoptosis, respectively.

作者: Chiara Porta , Reda Hadj-Slimane , Mohamed Nejmeddine , Mathieu Pampin , Michael G Tovey

DOI: 10.1038/SJ.ONC.1208204

关键词:

摘要: Type I interferon (IFN) enhances the transcription of the tumor suppressor gene p53. To elucidate the molecular mechanism mediating IFN-induced apoptosis, we analysed …

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