Colonization of the gut with Gram-negative bacilli, its association with neonatal sepsis and its clinical relevance in a developing country.

摘要: This study examined the pattern of colonization neonatal gut by aerobic Gram-negative bacilli (GNB) and evaluated association between sepsis in developing world. deserves attention because high incidence differences hygienic environments countries compared with developed The was carried out on neonates a tertiary-care government hospital. Serial samples were analysed (gastric aspirates stool samples) for GNB. Blood cases showing clinical signs also septic screening culture positivity. Antibiograms, serotyping PFGE to evaluate relatedness blood isolates. A diverse array GNB isolated from neonates, Klebsiella pneumoniae being most common, followed Escherichia coli. rate isolation consistently higher gastric aspirate samples. Colonization influenced stay intensive care unit prolonged use feeding tube. cause majority cases, K. frequently blood. Acinetobacter baumannii, coli, Enterobacter cloacae Burkholderia cepacia other recovered neonates. Neonates had than those without. In 50 % genotypes organisms found indistinguishable their counterpart. These results show that is colonized GNB, an observed.