Reduction of postmortem angiography-induced tissue edema by using polyethylene glycol as a contrast agent dissolver.
作者： Christian Jackowski , Stephan Bolliger , Emin Aghayev , Andreas Christe , Thomas Kilchoer
DOI: 10.1111/J.1556-4029.2006.00207.X
关键词:
摘要: Postmortem investigation is increasingly supported by computed tomography (CT) and magnetic resonance imaging, in which postmortem minimal invasive angiography has become important. The newly introduced approach using an aqueous contrast agent solution provided excellent vessel visualization but was suspected to possibly cause tissue edema artifacts histological investigations. aim of this study investigate on a porcine heart model whether it possible influence the distribution within soft changing its viscosity dissolving polyethylene glycol (PEG) as matrix medium. High-resolution CT scans after injection showed that viscosities above c. 15 mPa s (65% PEG) prevented capillary bed left ventricular myocardium. Thereby, precondition could be reduced. Its application human corpses needs further adapted flow resistance expected differ between different tissues.
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