Study of Thermal Degradation of PLGA, PLGA Nanospheres and PLGA/Maghemite Superparamagnetic Nanospheres
作者： Marcela Fernandes-Silva , Ana Adelina Winkler-Hechenleitner , Juan Manuel Irache , Adilson Jesús Aparicio-de-Oliveira , Edgardo Alfonso Gomez-Pineda
关键词:
摘要: Poly(glycolide-co-lactide) (PLGA) nanospheres containing magnetic materials have been extensively studied because of its biomedical applications. Therefore, it is very important to know thermal properties these in addition other physical properties. Thermal degradation activation energy (Eα) PLGA with maghemite entrapment (PLGA-Mag), (hollow spheres) (PLGA-H) obtained by an emulsion method and unprocessed (PLGA-R) were calculated isoconversional Vyazovkin based on data TG analysis order evaluate modifications behavior caused obtainment process or entrapment. Both hydrodynamic diameter the range 200-250 nm polydispersity index lower than 0.3 are considered satisfactory. PLGA-R begins at higher temperatures those PLGA-H PLGA-Mag, but processed samples presented increase stability, which was greater before processing presence materials. PLGA-Mag presents superparamagnetic room temperature.
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Daniele Rubert Nogueira, Laís E Scheeren, Letícia B Macedo, Ana Isa P Marcolino, M Pilar Vinardell, Montserrat Mitjans, M Rosa Infante, Ammad A Farooqi, Clarice MB Rolim, None, Inclusion of a pH-responsive amino acid-based amphiphile in methotrexate-loaded chitosan nanoparticles as a delivery strategy in cancer therapy Amino Acids. ,vol. 48, pp. 157- 168 ,(2016) , 10.1007/S00726-015-2075-1
Udo Schwertmann, Rochelle M. Cornell, The iron oxides: structure, properties, reactions, occurrences and uses. The iron oxides: structure, properties, reactions, occurrences and uses.. pp. 2664- ,(2003)
Ammad Ahmad Farooqi, Sundas Fayyaz, Iryna Shatynska-Mytsyk, Zeeshan Javed, Saima Jabeen, Ilhan Yaylim, Maria Luisa Gasparri, Pierluigi Benedetti Panici, Is miR-34a a Well-equipped Swordsman to Conquer Temple of Molecular Oncology? Chemical Biology & Drug Design. ,vol. 87, pp. 321- 334 ,(2016) , 10.1111/CBDD.12634
A. Aouad, L. Bilali, M. Benchanâa, A. Mokhlisse, Kinetic Aspect of Thermal Decomposition of Natural Phosphate and its Kerogen. Influence of heating rate and mineral matter Journal of Thermal Analysis and Calorimetry. ,vol. 67, pp. 733- 743 ,(2002) , 10.1023/A:1014329526885
Jie Shen, Diane J. Burgess, Accelerated in vitro release testing of implantable PLGA microsphere/PVA hydrogel composite coatings International Journal of Pharmaceutics. ,vol. 422, pp. 341- 348 ,(2012) , 10.1016/J.IJPHARM.2011.10.020
Marcela F Silva, Luiz AS de Oliveira, Mariani A Ciciliati, Lais T Silva, Bruna S Pereira, Ana Adelina W Hechenleitner, Daniela MF Oliveira, Kleber R Pirota, Flávio F Ivashita, Andrea Paesano, J Martin Pastor, J Iñaki Pérez-Landazábal, Edgardo AG Pineda, None, Nanometric particle size and phase controlled synthesis and characterization of γ-Fe2O3 or (α + γ)-Fe2O3 by a modified sol-gel method Journal of Applied Physics. ,vol. 114, pp. 104311- 104311 ,(2013) , 10.1063/1.4821253
Feng Wan, Adam Bohr, Morten Jonas Maltesen, Simon Bjerregaard, Camilla Foged, Jukka Rantanen, Mingshi Yang, Critical solvent properties affecting the particle formation process and characteristics of celecoxib-loaded plga microparticles via spray-drying. Pharmaceutical Research. ,vol. 30, pp. 1065- 1076 ,(2013) , 10.1007/S11095-012-0943-X
Marco Furlan, Johannes Kluge, Marco Mazzotti, Marco Lattuada, Preparation of biocompatible magnetite–PLGA composite nanoparticles using supercritical fluid extraction of emulsions Journal of Supercritical Fluids. ,vol. 54, pp. 348- 356 ,(2010) , 10.1016/J.SUPFLU.2010.05.010
Xiaolong Tang, Yong Liang, Xiaojun Feng, Rongbo Zhang, Xu Jin, Leilei Sun, Co-delivery of docetaxel and Poloxamer 235 by PLGA–TPGS nanoparticles for breast cancer treatment Materials Science and Engineering: C. ,vol. 49, pp. 348- 355 ,(2015) , 10.1016/J.MSEC.2015.01.033
Sinjan De, Dennis H. Robinson, Particle size and temperature effect on the physical stability of PLGA nanospheres and microspheres containing Bodipy AAPS PharmSciTech. ,vol. 5, pp. 18- 24 ,(2004) , 10.1208/PT050453