Demonstration of antibodies to collagen and of collagen-anticollagen immune complexes in rheumatoid arthritis synovial fluids
作者： J. Menzel , C. Steffen , G. Kolarz , R. Eberl , O. Frank
DOI: 10.1136/ARD.35.5.446
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摘要: Menzel, J., Steffen, C., Kolarz, G., Eberl, R., Frank, O., and Thumb, N. (1976).Annals of the Rheumatic Diseases, 35, 446-450. Demonstration antibodies to collagen collagen-anticollagen immune complexes in rheumatoid arthritis synovial fluids. Twenty-nine fluids from patients with (RA) 10 other joint diseases were investigated regard presence denatured human complexes. 12 29 RA showed anticollagen titres 1: 16 512 passive haemagglutination. Only one patient group no had a significant titre 32. Digestion bacterial collagenase resulted an increase two four dilution steps 9 fluids, while 6 previously negative 32 128 after digestion collagenase. These results indicate existence 15 investigated.
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