Protein parameters of differential gene activation during development and tumorigenesis.

摘要: Various models of normal and abnormal developmental systems were addressed to get an insight into molecular parameters cell differentiation at the level protein gene products. Electrophoretic analysis heterogeneous mixtures permitted qualitative developing systems, particularly during organogenesis in mammals, as well neoplastic growth animal plant kingdoms. From our earlier findings indicating that definite patterns characteristic adult organs are acquired long after morphological histological characteristics these tissues have developed, it has been repeatedly proven quantitative changes whole proteins is not a dependable indicator differentiation.