Industrial Melanism in British Peppered Moths Has a Singular and Recent Mutational Origin

摘要: The rapid spread of a novel black form (known as carbonaria) the peppered moth Biston betularia in 19th-century Britain is textbook example how an altered environment may produce morphological adaptation through genetic change. However, underlying basis difference between wild-type (light-colored) and carbonaria forms has remained unknown. We have genetically mapped morph to 200-kilobase region orthologous segment silkworm chromosome 17 show that there only one core sequence variant associated with morph, carrying signature recent strong selection. coincides major wing-patterning loci other lepidopteran systems, suggesting existence basal color-patterning regulators this region.