In utero pesticide exposure and childhood morbidity

摘要: In humans, immune development begins early in embryonic life and continues throughout the postnatal period. Although a number of pesticides have been observed to induce developmental immunotoxicity mice, few human studies examined long term effects utero pesticide exposure on childhood morbidity. Empirical evidence suggests that vulnerable period for toxic insults developing system extends from gestation adolescence humans animals. Using data Ontario Farm Family Health Study, we relationship between farm couple exposures during pregnancy subsequent health outcomes their offspring, including: persistent cough or bronchitis, asthma, allergies hayfever. No strong associations asthma were found. There was suggestive hayfever appeared be more common especially male exposed certain specific pregnancy. Nevertheless, given indirect indicators used this study, scarcity other child outcomes, these findings serve primarily generate hypotheses future research.