Links Between Injury-Induced Brain Remodeling and Oncogenesis

摘要: The remarkable progress achieved in the identification of potential cellular and molecular players neural tissue repair puts us at edge development therapeutic strategies that could effectively alleviate consequences CNS injuries. In face this novel hope, it appears timely to assess data derived from research on brain neoplasms. cell rearrangements initiated by injury nervous tissues are indeed characterized transient reacquisition features usually associated with cancer cells including genomic perturbations, reentrance into cycle, aberrant differentiation. All these changes can be viewed as intrinsic neoplastic reacting existence common between cells, developing immature mature brain, and/or injured has acknowledged order develop most appropriate strategies.