Drug treatment of Parkinson's disease.

作者: N. Quinn

DOI: 10.1136/BMJ.310.6979.575

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摘要: Summary points A wide variety of drugs is available for treating Parkinson9s disease, including anticholinergics, amantadine levodopa, dopamine agonists, and selegeline In younger patients ( 70) levodopa should be started as soon symptom relief required. Between these ages there no consensus, but at present most such probably given controlled release before a agonist added Fluctuations can often alleviated by giving preparations small doses frequent intervals, adding selegiline or long acting oral agonist, subcutaneous apomorphine Dyskinesia peak dose, diphasic, “off period.” The diphasic form hardest to alleviate Psychiatric side effects initially managed changing the antiparkinsonian treatment resorting antipsychotic

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