Confusion, dementia and anticholinergics in Parkinson's disease.
作者： Y de Smet , M Ruberg , M Serdaru , B Dubois , F Lhermitte
关键词: Levodopa 、 Internal medicine 、 Cholinergic 、 Confusion 、 Medicine 、 Parkinson's disease 、 Dementia 、 Anesthesia 、 Anticholinergic 、 Population 、 Hippocampus
摘要: Among a population of 75 hospitalised Parkinsonian subjects, confusional states were observed in 46% demented patients not receiving anticholinergic drugs and 93% under therapy. The sensitivity Parkinsonians to can be attributed cholinergic deficiency which has been detected the cortex hippocampus post-mortem. observations suggest that medication should avoided with intellectual impairment.
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