Capping of the Lymphocyte C3 Receptor and Temperature-Dependent Loss of C3 Rosettes

摘要: The percentage of mouse spleen cells rosetted by bacteria-antibody-complement complexes (BAC) was found to be temperature dependent. Maximal rosetting observed when BAC and were incubated in ice (0.5 degrees C), whereas less resulted from 37 C incubations. When at C, cap formation occur, indirect evidence suggested that the capped bacteria subsequently shed lymphocyte surface. Neither capping nor shedding occurred 0.5 suggesting these phenomena responsible for decreased after incubation C. An incidental observation indicated a second factor potentially contributing loss removal surface phagocytes.