Stimulation of Tissue Regeneration by Pulsed Plane-Wave Ultrasound

摘要: Plane-wave ultrasound at certain dosages can cause a statistically significant increase in the rate which tissue re- generates to replace that lost after injury. The experimental model used this study is replacement of pinna ear rabbit removal area 1 cm2 through full thickness ear. regenerate consists skin and its derivatives elastic cartilage. method irradiation effects range on are described. Experimental evidence indicates growth increases found not due thermal caused by ultrasound; it thought mechanical factor, streaming, may be involved. Electron microscopic studies show changes irradiated interpreted as indicating an protein synthesis temporary interference with polymerization collagen precursors. Autoradiographic investigation 3H-thymidine uptake shows DNA regenerating increased treatment ultrasound. ISTROUL-CTIOX HERE have been several reports enzyme activity (l), (2) thus generally metabolic ac- tivity. In plants effect stimulates seed germination young seedlings (3), (4). This stimulation plant suggested use ultra- sound possible stimulant animals. control regenerative growth, i.e., tissue, clinically important injuries post-operative care. It stimulate systemic means, for example, repeated injection anabolic hormones (5), but such affects other sites well produce undesirable side effects. direct