The effect of ultrasound on microvascular hemodynamics in skeletal muscle: effect on arterioles

作者: R.D. Hogan , T.D. Franklin , F.J. Fry , K.A. Avery , K.M. Burke

DOI: 10.1016/0301-5629(82)90068-0

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摘要: A skeletal muscle model (rat cremaster muscle) has been described for the evaluation of ultrasonic bioeffects on microscopic vasculature. One MHz pulsed ultrasound (mark-space 100tzsec:100/~sec) was administered to tissue at 1.25, 2.5, 5.0 and 10.0Wcm -2 (temporal average) while continuously measuring lumen diameter, volume flow, rate vasomotion (intrinsic cyclic constriction relaxation) in three different sizes arterioles (100, 50, 30 #m inner diameter). No change these parameters noted intensities below 5 Wcm -2. Above there a 25% decrease diameter 44% flow smallest observed, as well 29% largest arteriole feeding tissue. The increased 20x same intensity range. None effects or their magnitude could be attributed simple heating temperature range t34-36.5°C) obtained with exposures.

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