Continuous performance test in pediatric obsessive-compulsive disorder and tic disorders: the role of sustained attention

摘要: Objective Pediatric obsessive-compulsive disorder (OCD) and tic disorders (TD) are often associated with attention-deficit hyperactivity (ADHD). In order to clarify the role of attention inhibitory control in pediatric OCD TD, a continuous performance test (CPT) was administered cohort children adolescents alone, TD OCD+TD. Methods A clinical 48 alone (n = 20), 15), or OCD+TD 13) interviewed clinically Conners Continuous Performance Test II (CPT-II). The CPT-II is 14-minute normed computerized consisting 6 blocks. It taps into attention, control, sustained cognitive domains. Key parameters include errors omission (distractability), commission (inhibitory control), variable responding over time (sustained attention). Diagnostic Statistical Manual Mental Disorders , 4th Edition (DSM-IV) criteria were applied best-estimate process diagnose OCD, ADHD, anxiety disorders. Results Children had more ( p 0.03), hit RT block change 0.003) SE 0.02) than subjects alone. These deficits younger age hoarding tendencies. diagnosis ADHD group also determined worse attention. Conclusions deficit core marker OCD+TD, compared Biological correlates may serve uncover pathophysiology through genetic imaging studies.