Human embryonal epithelial cells of the developing small intestinal crypts can express the Hodgkin-cell associated antigen Ki-1 (CD30) in spontaneous abortions during the first trimester of gestation
作者： Demetrio Tamiolakis , John Venizelos , Maria Lambropoulou , Silva Nikolaidou , Sophia Bolioti
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摘要: Background Ki-1 (CD30) antigen expression is not found on peripheral blood cells but its can be induced in vitro T and B lymphocytes by viruses lectins. Expression of CD30 normal tissues very limited, being restricted mainly to a subpopulation large lymphoid cells; particular, the recently described anaplastic cell lymphoma (ALCL), Reed-Sternberg (RS) Hodgkin's scattered parafollicular tissues. More recent reports have non-hematopoietic malignant such as cultured human macrophages, decidual cells, histiocytic neoplastic mesothelioma embryonal carcinoma seminoma cells.
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