Cardiac Troponins I and T: Molecular Markers for Early Diagnosis, Prognosis, and Accurate Triaging of Patients with Acute Myocardial Infarction
作者： Ram P. Tiwari , Anubhav Jain , Zakir Khan , Veena Kohli , R. N. Bharmal
DOI: 10.1007/S40291-012-0011-6
关键词:
摘要: Acute myocardial infarction (AMI) is the leading cause of death worldwide, with early diagnosis still being difficult. Promising new cardiac biomarkers such as troponins and creatine kinase (CK) isoforms are studied integrated into clinical practice for AMI. The cardiac-specific I T (cTnI cTnT) have good sensitivity specificity indicators necrosis superior to CK its MB isoenzyme (CK-MB) in this regard. Besides potential biologic markers, also provide significant prognostic information. introduction novel high-sensitivity troponin assays has enabled more sensitive timely or exclusion acute coronary syndromes. This review summarizes available information on other markers prognosis AMI, provides perspectives future diagnostic approaches
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