Introduction to Coronary Artery Disease (CAD) and Biochemical Markers

摘要: Cardiovascular disease (CVD) (of which CAD is a subset) the leading cause of morbidity and mortality in Western world. In US, there are approx 70 million people who suffer from one form this or another (Fig. 1) (1). Each year, 500,000 stroke (cerebrovascular accident, CVA). The annual rate CVA about 150,000 individually ranks third overall behind acute myocardial infarction (AMI) (discussed Chapter 3) cancer. Approximately six Americans admitted to hospitals with diagnosis chest pain. Of those individuals CVD, roughly 5% (three million) have silent ischemia. incidence AMI combination patients symptomatic asymptomatic (silent) 1.5 patients/yr. 500,000/yr. Half these deaths occur before they reach hospital for treatment. Unstable angina 2) congestive heart failure (CHF) account large fraction non-AMI A number pain also inappropriately noncardiac causes. remainder discharged home. From group, 30,000 emergency department. 4 discusses impact that cardiac markers on discharge