作者: Massimo Franchini , Pier Mannuccio Mannucci
DOI: 10.1111/J.1365-2141.2009.08005.X
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摘要: The life expectancy and quality of persons with haemophilia has dramatically increased since the 1970s, exception rate deaths observed during 1980s 1990s due to blood-borne viral infections. Improvements factor replacement therapy, treatment infectious diseases comprehensive health care provided by specialised centres are main determinants increasing age population. As a consequence, growing number these patients develop age-related co-morbidities, such as cardiovascular disease cancer. previously rare conditions is new challenge for caregivers in centres. This review focuses on co-morbidities ageing patients, their impact complex management.