Imidazolo-quinoxalinones for treating diseases of the central nervous system

作者: Hans-Joerg Treiber , Hans Peter Hofmann , Berthold Behl

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摘要: Imidazolo-quinoxalinones are used for preparing medicaments treating diseases of the central nervous system. The imidazolo-quinoxalinones have formula (I), in which R1, R2 and X meanings given description.

参考文章(9)
Ian R. Ager, Alan C. Barnes, Geoffrey W. Danswan, Peter W. Hairsine, David P. Kay, Peter D. Kennewell, Saroop S. Matharu, Peter Miller, Peter Robson, Synthesis and oral antiallergic activity of carboxylic acids derived from imidazo[2,1-c][1,4]benzoxazines, imidazo[1,2-a]quinolines, imidazo[1,2-a]quinoxalines, imidazo[1,2-a]quinoxalinones, pyrrolo[1,2-a]quinoxalinones, pyrrolo[2,3-a]quinoxalinones, and imidazo[2,1-b]benzothiazoles. Journal of Medicinal Chemistry. ,vol. 31, pp. 1098- 1115 ,(1988) , 10.1021/JM00401A009
Tage Honoré, Flemming Elmelund Nielsen, Poul Jacobsen, Jorgen Drejer, Fused dihydroxyquinoxalines and their use as glutamate antagonists ,(1989)
Loretta Ames Mcquaid, Paul Leslie Ornstein, Charles Howard Mitch, Edward C. R. Smith, Darryle Darwin Schoepp, Improvements in or relating to excitatory amino acid receptor antagonists ,(1992)
Jun-Ya Ohmori, Masamichi Okada, Kazyuki Hidaka, Shuichi Sakamoto, Masao Sasamata, Fused quinoxalinone derivative and pharmaceutical composition containing the same ,(1993)
Loretta A. McQuaid, Edward C. R. Smith, Kimberly K. South, Charles H. Mitch, Darryle D. Schoepp, Rebecca A. True, David O. Calligaro, Patrick J. O'Malley, David Lodge, Paul L. Ornstein, Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones Journal of Medicinal Chemistry. ,vol. 35, pp. 3319- 3324 ,(1992) , 10.1021/JM00096A002