Oligoribonucleotide or peptide nucleic acid capable of inhibiting activity of hepatitis c virus
作者： Masayuki Sudo , Michinori Kohara
DOI:
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摘要: The present inventors focused on siE sequences that have been thought to show RNAi activity against HCV viral RNAs, and mainly selected the D5-50 D5-197 regions within IRES region, carried analysis. As a result, successfully identified siRNA exhibit more effective hepatitis C virus RNAs. Furthermore, siRNAs were demonstrated significant inhibitory effect propagation in an vivo system.
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