Stress-induced endocrine response and anxiety: the effects of comfort food in rats.

作者: Daniela Ortolani , Márcia Carvalho Garcia , Liana Melo-Thomas , Regina Celia Spadari-Bratfisch

DOI: 10.3109/10253890.2014.898059

关键词:

摘要: The long-term effects of comfort food in an anxiogenic model stress have yet to be analyzed. Here, we evaluated behavioral, endocrine and metabolic parameters rats submitted or not chronic unpredictable mild (CUMS), with access commercial chow alone food. Stress did alter the preference for but decreased intake. In elevated plus-maze (EPM) test, stressed were less likely enter/remain open arms, as well being more closed than control rats, both conditions pronounced given field time spent centre, independent diet; neither nor diet affected number crossing, rearing grooming episodes. stress-induced increase serum corticosterone was attenuated Serum concentration triglycerides unaffected by diet, although increased total cholesterol glucose. It is concluded that CUMS has anorexigenic effect. Chronic ingestion induced profile response. present data indicate combination food, common aspects modern life, may constitute a link among stress, feeding behavior anxiety.

参考文章(57)
F. Kiefer, M. Grosshans, Beitrag der Suchtforschung zum Verständnis der Adipositas Nervenarzt. ,vol. 80, pp. 1040- 1049 ,(2009) , 10.1007/S00115-009-2743-Z
P.E. Sawchenko, E.R. Brown, R.K.W. Chan, A. Ericsson, H.-Y. Li, B.L. Roland, K.J. Kovács, Chapter 12 The paraventricular nucleus of the hypothalamus and the functional neuroanatomy of visceromotor responses to stress Progress in Brain Research. ,vol. 107, pp. 201- 222 ,(1996) , 10.1016/S0079-6123(08)61866-X
P.E. Sawchenko, H.-Y. Li, A. Ericsson, Circuits and mechanisms governing hypothalamic responses to stress: a tale of two paradigms. Progress in Brain Research. ,vol. 122, pp. 61- 78 ,(2000) , 10.1016/S0079-6123(08)62131-7
Ali Rashidy-Pour, Abbas Ali Taherian, Abbas Ali Vafaei, Peripheral injection of dexamethasone modulates anxiety related behaviors in mice: an interaction with opioidergic neurons. Pakistan Journal of Pharmaceutical Sciences. ,vol. 21, pp. 285- 289 ,(2008)
Bruce S. McEwen, Peter J. Gianaros, Central role of the brain in stress and adaptation: Links to socioeconomic status, health, and disease Annals of the New York Academy of Sciences. ,vol. 1186, pp. 190- 222 ,(2010) , 10.1111/J.1749-6632.2009.05331.X
J L Moreau, J R Martin, P Mortas, F Jenck, A Bourson, Curative effects of the atypical antidepressant mianserin in the chronic mild stress-induced anhedonia model of depression Journal of Psychiatry & Neuroscience. ,vol. 19, pp. 51- 56 ,(1994)
Stephen C. Woods, Randy J. Seeley, Paul A. Rushing, David D'Alessio, Patrick Tso, A Controlled High-Fat Diet Induces an Obese Syndrome in Rats Journal of Nutrition. ,vol. 133, pp. 1081- 1087 ,(2003) , 10.1093/JN/133.4.1081
Laetitia Prut, Catherine Belzung, The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review European Journal of Pharmacology. ,vol. 463, pp. 3- 33 ,(2003) , 10.1016/S0014-2999(03)01272-X
Shuwen Liang, Donna M. Byers, Louis N. Irwin, Sex and diet affect the behavioral response of rats to chronic mild stressors Physiology & Behavior. ,vol. 93, pp. 27- 36 ,(2008) , 10.1016/J.PHYSBEH.2007.07.007