Multilocus sequence typing of hospital-associated Enterococcus faecium from Brazil reveals their unique evolutionary history.

作者: Ricardo Titze-De-Almeida , Alex Van Belkum , Maria Sueli Soares Felipe , Rosemeire C. Zanella , Janetta Top

DOI: 10.1089/MDR.2006.12.121

关键词:

摘要: We studied the genetic relationships between vancomycin-susceptible (n = 11) and -resistant Enterococcus faecium (VRE, n 20) recovered from Brazil using a multilocus sequence typing (MLST) scheme. Grouping of allelic profiles revealed six clusters related types (STs) that differ in no more than two seven alleles. Of these, one cluster harbored 16 20 isolates during first VRE outbreak Brazil. The ampicillin gentamicin resistance were stable clustered within groups I-III. Comparison with 139 E. different geographical regions origins found international database http://www.mlst.net Brazilian clone did not previously named complex-17. This complex contains hospital epidemic clinical countries continents. Twenty 31 isolates, including clone, apart database, suggesting these have distinct evolutionary history.

参考文章(24)
J.C.R. Cordeiro, S. Silbert, A.O. Reis, H.S. Sader, Inter-hospital dissemination of glycopeptide-resistant Enterococcus faecalis in Brazil. Clinical Microbiology and Infection. ,vol. 10, pp. 260- 262 ,(2004) , 10.1111/J.1198-743X.2004.00866.X
K. S. Ko, J. Y. Baek, J.-Y. Lee, W. S. Oh, K. R. Peck, N. Lee, W. G. Lee, K. Lee, J.-H. Song, Molecular Characterization of Vancomycin-Resistant Enterococcus faecium Isolates from Korea Journal of Clinical Microbiology. ,vol. 43, pp. 2303- 2306 ,(2005) , 10.1128/JCM.43.5.2303-2306.2005
D F Sahm, J Kissinger, M S Gilmore, P R Murray, R Mulder, J Solliday, B Clarke, In vitro susceptibility studies of vancomycin-resistant Enterococcus faecalis. Antimicrobial Agents and Chemotherapy. ,vol. 33, pp. 1588- 1591 ,(1989) , 10.1128/AAC.33.9.1588
A. H. C. Uttley, R. C. George, J. Naidoo, N. Woodford, A. P. Johnson, C. H. Collins, D. Morrison, A. J. Gilfillan, L. E. Fitch, J. Heptonstall, High-level vancomycin-resistant enterococci causing hospital infections Epidemiology and Infection. ,vol. 103, pp. 173- 181 ,(1989) , 10.1017/S0950268800030478
Marc JM Bonten, Rob Willems, Robert A Weinstein, Vancomycin-resistant enterococci: why are they here, and where do they come from? Lancet Infectious Diseases. ,vol. 1, pp. 314- 325 ,(2001) , 10.1016/S1473-3099(01)00145-1
Roland Leclercq, Eliane Derlot, Jean Duval, Patrice Courvalin, Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium. The New England Journal of Medicine. ,vol. 319, pp. 157- 161 ,(1988) , 10.1056/NEJM198807213190307
Yasuyoshi Ike, Koichi Tanimoto, Yoshiyuki Ozawa, Takahiro Nomura, Shuhei Fujimoto, Haruyoshi Tomita, Vancomycin-resistant enterococci in imported chickens in Japan. The Lancet. ,vol. 353, pp. 1854- ,(1999) , 10.1016/S0140-6736(99)01060-0
Leo M. Schouls, Han G. J. van der Heide, Luc Vauterin, Paul Vauterin, Frits R. Mooi, Multiple-Locus Variable-Number Tandem Repeat Analysis of Dutch Bordetella pertussis Strains Reveals Rapid Genetic Changes with Clonal Expansion during the Late 1990s Journal of Bacteriology. ,vol. 186, pp. 5496- 5505 ,(2004) , 10.1128/JB.186.16.5496-5505.2004