Role of the Plasminogen Activator-Plasmin System in Angiogenesis
作者： Michael S. Pepper
DOI: 10.1007/978-1-4615-0165-7_16
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摘要: It is firmly established that angiogenesis an absolute requirement for the growth of normal and neoplastic tissues (Pepper, 1997). Many biological processes, including angiogenesis, depend on tightly controlled interactions between cells extracellular matrix (ECM). These are mediated (a) by integral membrane proteins integrins, which provide a link ECM cytoskeleton; (b) proteinases their inhibitors, mediate focal degradation components ECM, some (e.g., fibrillar collagens) highly resistant to broad spectrum proteases. Most relevant proteolytic enzymes belong one two families: serine proteases, in particular plasminogen activator (PA)/plasmin system, metalloproteinases (MMPs) (Mignatti Rifkin, 1996; Pepper, 2001a; Vu Werb, 2000).
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sci-hub.st 参考文章(143)
DANIELA K. ZABLOCKI, JEFFREY J. RADE, B. RITA ALEVRIADOU, ADENOVIRUS-MEDIATED EXPRESSION OF TISSUE PLASMINOGEN ACTIVATOR DOES NOT ALTER ENDOTHELIAL CELL PROLIFERATION AND INVASION In Vitro Cellular & Developmental Biology – Animal. ,vol. 36, pp. 625- 628 ,(2000) , 10.1290/1071-2690(2000)036<0625:AMEOTP>2.0.CO;2
Corinne Rosnoblet, Corinne Di Sanza, Egbert Kruithof, Michael Pepper, Synergistic induction of t-PA by vascular endothelial growth factor and basic fibroblast growth factor and localization of t-PA to Weibel-Palade bodies in bovine microvascular endothelial cells. Thrombosis and Haemostasis. ,vol. 86, pp. 702- 709 ,(2001) , 10.1055/S-0037-1616107
Michael Pepper, Extracellular proteolysis and angiogenesis. Thrombosis and Haemostasis. ,vol. 86, pp. 346- 355 ,(2001) , 10.1055/S-0037-1616232
Yihai Cao, Therapeutic potentials of angiostatin in the treatment of cancer. Haematologica. ,vol. 84, pp. 643- 650 ,(1999) , 10.3324/%X
Robert W Colman, Bradford A Jameson, Yingzhang Lin, Donald Johnson, Shaker A Mousa, None, Domain 5 of high molecular weight kininogen (kininostatin) down-regulates endothelial cell proliferation and migration and inhibits angiogenesis Blood. ,vol. 95, pp. 543- 550 ,(2000) , 10.1182/BLOOD.V95.2.543
Yvonne H. Datta, Hagop Youssoufian, Peter W. Marks, Bruce M. Ewenstein, Targeting of a heterologous protein to a regulated secretion pathway in cultured endothelial cells. Blood. ,vol. 94, pp. 2696- 2703 ,(1999) , 10.1182/BLOOD.V94.8.2696.420K29_2696_2703
HI Ma, SZ Lin, YH Chiang, J Li, SL Chen, YP Tsao, X Xiao, None, Intratumoral gene therapy of malignant brain tumor in a rat model with angiostatin delivered by adeno-associated viral (AAV) vector. Gene Therapy. ,vol. 9, pp. 2- 11 ,(2002) , 10.1038/SJ.GT.3301616
MG Sacco, E Mira Catò, R Ceruti, S Soldati, S Indraccolo, M Caniatti, E Scanziani, P Vezzoni, Systemic gene therapy with anti-angiogenic factors inhibits spontaneous breast tumor growth and metastasis in MMTVneu transgenic mice. Gene Therapy. ,vol. 8, pp. 67- 70 ,(2001) , 10.1038/SJ.GT.3301358
Luca Primo, Cristina Roca, Chiara Ferrandi, Luisa Lanfrancone, Federico Bussolino, Human endothelial cells expressing polyoma middle T induce tumors. Oncogene. ,vol. 19, pp. 3632- 3641 ,(2000) , 10.1038/SJ.ONC.1203708
Monica Rodolfo, Enrica Mira Catò, Sabina Soldati, Roberta Ceruti, Marco Asioli, Eugenio Scanziani, Paolo Vezzoni, Giorgio Parmiani, Maria Grazia Sacco, Growth of human melanoma xenografts is suppressed by systemic angiostatin gene therapy. Cancer Gene Therapy. ,vol. 8, pp. 491- 496 ,(2001) , 10.1038/SJ.CGT.7700331