A naturalistic retrospective analysis of psychostimulants in pervasive developmental disorders.
作者： Kimberly A. Stigler , Lael A. Desmond , David J. Posey , Ryan E. Wiegand , Christopher J. McDougle
DOI: 10.1089/104454604773840481
关键词:
摘要: Objective: We set out to examine the effectiveness and tolerability of psychostimulants in children adolescents with pervasive developmental disorders (PDDs). Methods: Medical records all patients PDDs treated a stimulant were retrospectively reviewed. Demographics, type, drug dosage, trial duration, adverse effects recorded. Global improvement, focused on symptoms hyperactivity inattention, was measured by Clinical Impressions-Improvement scale, positive response defined rating much improved or very improved. Results: Of 195 (174 males, 21 females; mean age ± SD = 7.26 3.45 years, range 2-19 years), 61 had more than one trial, resulting total 274 separate trials. It discovered that 24.6%, 23.2%, 11.1% history one, two, three trials, respectively, responded their first trial. Among nonresponders, 6 (14.0%) 43 sec...
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