Primary combined hepatocellular-cholangiocellular sarcoma: An unusual case

作者: Shuai Xiang , Yi-Fa Chen , Yan Guan , Xiao-Ping Chen

DOI: 10.3748/WJG.V21.I23.7335

关键词:

摘要: Primary liver carcinosarcoma is rare. Here we report an unusual case of containing combined hepatocellular cholangiocarcinoma. A mass in the right lobe a 45-year-old man was accidentally discovered by ultrasonic inspection and computed tomography (CT) scan. Surgical resection performed following diagnosis primary cancer. Micropathologically, both carcinomatous sarcomatous elements were present, confirmed. The element consisted carcinoma foci cholangiocellular carcinoma. composed spindle cells bizarre cells, as well osteosarcoma chondrosarcoma. Hepatocellular diffusely expressed hepatocyte specific markers cytokeratin (CK) 8/18 cholangiocyte CK19, sarcoma positive for vimentin. Interestingly, epithelial membrane antigen. CD117-positive ductular reactions small undifferentiated observed. progenitor cell origin proposed.

参考文章(26)
G B Levi Sandri, Q Lai, U Di Tondo, N Guglielmo, F Melandro, M Di Laudo, M Garofalo, M Grieco, M Rossi, P B Berloco, An unusual case of hepatic carcinosarcoma. Il Giornale di chirurgia. ,vol. 32, pp. 372- 373 ,(2011)
Progenitor cells in diseased human liver. Seminars in Liver Disease. ,vol. 23, pp. 385- 396 ,(2003) , 10.1055/S-2004-815564
M. Auxiliadora Aparicio, Carmen Esteban, Óscar Bengoechea, Luis Muñoz-Bellvís, Carcinosarcoma primario hepático: un caso excepcional con componentes epitelial y mesenquimal nítidamente separados Revista Espanola De Enfermedades Digestivas. ,vol. 103, pp. 336- 338 ,(2011) , 10.4321/S1130-01082011000600014
Qi-Bo Wang, Bo-Kang Cui, Jian-Ming Weng, Qiu-Liang Wu, Ji-Liang Qiu, Xiao-Jun Lin, Clinicopathological characteristics and outcome of primary sarcomatoid carcinoma and carcinosarcoma of the liver Journal of Gastrointestinal Surgery. ,vol. 16, pp. 1715- 1726 ,(2012) , 10.1007/S11605-012-1946-Y
Takatsugu Yamamoto, Yukiko Kurashima, Kazunori Ohata, Ryoya Hashiba, Shogo Tanaka, Takahiro Uenishi, Koichi Ohno, Takashi Ikebe, Katsuhiko Miyaji, Nobusuke Fukumoto, Carcinosarcoma of the liver: report of a case Surgery Today. ,vol. 44, pp. 1161- 1170 ,(2014) , 10.1007/S00595-013-0612-7
Chang-Hai Li, Yan-Jun Wang, Wei Dong, Shuai Xiang, Hui-Fang Liang, Heng-Yi Wang, Han-Hua Dong, Lin Chen, Xiao-Ping Chen, None, Hepatic oval cell lines generate hepatocellular carcinoma following transfection with HBx gene and treatment with aflatoxin B1 in vivo Cancer Letters. ,vol. 311, pp. 1- 10 ,(2011) , 10.1016/J.CANLET.2011.05.035
Han-Hua Dong, Shuai Xiang, Xiao-Ping Chen, Hui-Fang Liang, Wei Zhang, Kai Jing, Wei Zhang, Wan-Guang Zhang, Lin Chen, The Epithelial–Mesenchymal Transition Promotes Transdifferentiation of Subcutaneously Implanted Hepatic Oval Cells Into Mesenchymal Tumor Tissue Stem Cells and Development. ,vol. 18, pp. 1293- 1298 ,(2009) , 10.1089/SCD.2008.0321
Kumi Aita, Kunihiko Seki, Carcinosarcoma of the liver producing granulocyte-colony stimulating factor Pathology International. ,vol. 56, pp. 413- 419 ,(2006) , 10.1111/J.1440-1827.2006.01979.X