Promoter methylation in head and neck tumorigenesis.
作者： Josena K. Stephen , Kang Mei Chen , Shaleta Havard , Glynis Harris , Maria J. Worsham
DOI: 10.1007/978-1-61779-612-8_11
关键词:
摘要: In addition to genetic alterations of gains and losses, epigenetic events promoter methylation appear further undermine a destabilized genomic repertoire in squamous head neck carcinoma (HNSCC). This chapter provides an overview frequently methylated tumor suppressor genes benign papillomas, primary HNSCC tumors, cell lines their relevance as markers tumorigenesis.
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