Diastolic Hypotension in a Tertiary Care Hypertension Clinic: Have We Gone Too Far?
作者： Trevor Mace-Brickman , Wilder Leduc , Swapnil Hiremath , Marcel Ruzicka , Brendan B. McCormick
DOI: 10.1016/J.CJCA.2015.08.026
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摘要: Abstract Background Treatment-induced diastolic hypotension has been associated with an increased risk of adverse cardiovascular events in post hoc analyses major blood pressure (BP)-lowering trials. We undertook this retrospective study to assess the prevalence and factors for among patients referred a tertiary care hypertension clinic. Methods Charts all active were reviewed, BP at initial visit was compared first which systolic target achieved or last if not achieved. Diastolic defined as Results Four hundred sixty-six identified. The mean baseline 142/77 mm Hg, number medications 2.9. Forty-nine (10.5%) had baseline, further 68 (16%) acquired it during follow-up. Those no change antihypertensive being taken on follow-up (mean, 3.6-3.7; P = 0.46), did (53-55 Hg; 0.07). On adjusted analysis, older age (odds ratio [OR], 1.04; 0.0008), diabetes (OR, 2.8; 0.002), higher 1.03; Conclusions Treating resulted 27% followed Its presence does usually result reduction therapy. Older patients, diabetes, isolated appear be more susceptible development
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