Pityriasis Rosea, Gianotti-Crosti Syndrome, Asymmetric Periflexural Exanthem, Papular-Purpuric Gloves and Socks Syndrome, Eruptive Pseudoangiomatosis, and Eruptive Hypomelanosis: Do Their Epidemiological Data Substantiate Infectious Etiologies?

摘要: Many clinical and laboratory-based studies have been reported for skin rashes which may be due to viral infections, namely pityriasis rosea (PR), Gianotti-Crosti syndrome (GCS), asymmetric periflexural exanthem/unilateral laterothoracic exanthem (APE/ULE), papular-purpuric gloves socks (PPGSS), eruptive pseudo-angiomatosis (EP). Eruptive hypomelanosis (EH) is a newly discovered paraviral rash. Novel tools are now available investigate the epidemiology of these rashes. To retrieve epidemiological data exanthema analyze whether such substantiates or refutes infectious etiologies. We searched articles published over last 60 years indexed by PubMed database. then analyzed them universality, demography, concurrent patients, temporal spatial-temporal clustering, mini-epidemics, epidemics, other geographical associations. Based on our criteria, we selected 55, 60, 29, 36, 20, 4 PR, GCS, APE/ULE, PPGSS, EP, EH respectively. Universality multiple-continental reports found all except EH. The ages patients compatible with causes Concurrent all. Significant patient clustering demonstrated PR GCS. Mini-epidemics epidemics current supports, moderate extent, that APE could caused agents. Support PPGSS marginal. Epidemiological evidences origins EP inadequate. There might growing evidence substantiate refute findings in future.