A review of 32 cases of tardive dystonia.

摘要: Objective: Tardive dystonia, historically combined with tardive dyskinesia, is now viewed as probably having a different pathophysiology, course, outcome, and treatment response than dyskinesia. In addition, patients dystonia are reported to be younger, most men. This study evaluates characteristics of 32 compares results other reports. Method: Twenty-four had been referred for research purposes were videotaped, while eight followed clinically. Two ofthe authors reviewed all available videotapes clinical reports assess the course ofsymptoms over time. For global ratings ofaffected body parts, two scales used: Abnormal Involuntary Movement Scale (AIMS) dyskinesia similar scale dystonia. The method case finding does not provide incidence or preyalence data Results: Fifty-nine percent experienced onset symptoms within 6 years antipsychotic drug exposure; women shorter exposure No patient complete remission oftardive symptoms, 22 moderately severely impaired when their movements prominent. Conclusions: While epidemiological studies have yet performed, these support observations others that men, short history ofexposure drugs, may initially present blepharospasm. rarely remits completely, can cause notable disability, partially respond anticholinergic agents. (Am J Psychiatry 1991; 148:1055-1059) T ardive disorder abnormally sustamed posturing associated use dopamine-receptor blocking agents such drugs. Although chronic was first recognized in 1960s,