Acute renal failure in hospitalized patients with HIV : risk factors and impact on in-hospital mortality

摘要: Background: Kidney disease is an increasingly important complication of HIV. Objectives: To examine the incidence and predictors acute renal failure before after introduction HAART, impact on in-hospital mortality in post-HAART era. Methods: Adults hospitalized care hospitals New York State during 1995 (pre-HAART) or 2003 (post-HAART) were identified from state Planning Research Cooperative System database. HIV status was defined by primary secondary diagnosis code. The HAART mortality, assessed using Χ 2 analysis multivariate regression. Results: There 52 580 HIV-infected patients discharged hospital 25 114 2003. Compared with uninfected patients, had increased both pre-HAART [adjusted odds ratio (OR), 4.62; 95% confidence interval (Cl), 4.30-4.95] eras (adjusted OR, 2.82; Cl, 2.66-2.99). In cohort, associated traditional such as age, diabetes mellitus, chronic kidney disease, well liver hepatitis coinfection (P < 0.001 for all comparisons). Acute among era (OR, 5.83; 5.11-6.65). Conclusions: remains common mortality.