Diabetes mellitus: influences on cancer risk.

摘要: Diabetes mellitus and cancer are common conditions, their co-diagnosis in the same individual is not infrequent. The relative risks associated with type 2 diabetes greater than twofold for hepatic, pancreatic, endometrial cancers. risk somewhat lower, at 1.2-1.5-fold colorectal, breast, bladder In comparison, of lung less 1. evidence other malignancies (e.g. kidney, non-Hodgkin lymphoma) inconclusive, whereas prostatic occurs frequently male patients diabetes. potential biologic links between two diseases incompletely understood. Evidence from observational studies suggests that some medications used to treat hyperglycemia either increased or reduced cancer. Whereas anti-diabetic drugs have a minor influence on risk, may cause worsen pre-existing If hyperinsulinemia acts as critical link observed diabetes, one would predict 1 different pattern because former exposed lower levels exogenous administered insulin. Obtained results showed had elevated cancers stomach, cervix, endometrium. Type modest excess overall specific differ those