BISPECIFIC ANTIBODIES AGAINST CD3ε AND BCMA
作者： Anne Freimoser-Grundschober , Tanja Fauti , Marina Bacac , Klaus Strein , Ralf Hosse
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摘要: A bispecific antibody specifically binding to the two targets human CD3ɛ and BCMA, wherein variable domains of one portion are replaced by each other, characterized in that said is not reduced APRIL BAFF, does alter APRIL-dependent NF-κB activation, BAFF-dependent NF- κ B activation without BAFF useful as a therapeutic agent.
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