The effect of biomaterials and antifungals on biofilm formation by Candida species: a review.

摘要: Candida albicans, C. glabrata, parapsilosis, and tropicalis are able to form biofilms on virtually any biomaterial implanted in a human host. Biofilms primary cause of mortality immunocompromised hospitalized patients, as they recurrent invasive candidiasis, which is difficult eradicate. This due the fact that biofilm cells show high resistance antifungal treatments host defense mechanisms, exhibit an excellent ability adhere biomaterials. Elucidation mechanisms unquestionable importance; therefore, this review analyzes both chemical composition biomaterials used fabricate medical devices, well genes proteins confer drug resistance.