In vivo imaging of tumor growth after electrochemotherapy with cisplatin.
作者： Maja Cemazar , Muriel Golzio , Jean-Michel Escoffre , Bettina Couderc , Gregor Sersa
DOI: 10.1016/J.BBRC.2006.07.132
关键词:
摘要: Imaging methods can give both temporal and spatial dimensions to characterize the processes in progression of and/or treatment specific disease Subcutaneous tumors be cured after electrochemotherapy (ECT). Growth reduction as a result cytotoxic therapy followed by fluorescence video imaging directly on same animal treatment. should bring more information cellular effects ECT. Green fluorescent protein (eGFP) expressing B16F10 LPB implanted C57Bl/6 mice were treated with ECT cisplatin. The growth or regression was monitored either classically using caliper manual definition region interest where critical levels detected animals. A very good correlation between two observed. eGFP mean emission only slightly affected intravenously injected Ex vivo observations under microscope showed that outer layer tumor. No central part tumors, which necrotic.
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