Templated solvothermal synthesis of magnesium silicate hollow nanospheres with ultrahigh specific surface area and their application in high-performance protein adsorption and drug delivery
作者： Tuan-Wei Sun , Ying-Jie Zhu , Chao Qi , Feng Chen , Ying-Ying Jiang
DOI: 10.1039/C5TB02632F
关键词:
摘要: Magnesium silicate nanostructured biomaterials with good biocompatibility and high adsorption capacity for drugs proteins are promising applications in various biomedical fields. However, the of magnesium anticancer drug delivery protein have rarely been reported so far. Herein, we report a facile strategy synthesis hollow nanospheres (MSHNSs) by classical Stober method template based solvothermal process. The as-prepared MSHNSs an ultrahigh specific surface area 585.6 m2 g−1, hemoglobin (Hb) (1262 mg g−1) doxorubicin (DOX) loading (559 g−1). Moreover, MSHNS/DOX system exhibits sustained pH-responsive release performance. Compared free DOX, higher activity vitro, thus it is treatment.
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