Esophageal Cancer: Genomic and Molecular Characterization, Stem Cell Compartment and Clonal Evolution.

Jingchuan Zhang, Dongxian Jiang, Xiaojing Li, Jing Lv, Liang Xie, Li Zheng, Paul R Gavine, Qin Hu, Yuan Shi, Lijie Tan, Di Ge, Songtao Xu, Leon Li, Lifang Zhu, Yingyong Hou, Qun Wang, Establishment and characterization of esophageal squamous cell carcinoma patient-derived xenograft mouse models for preclinical drug discovery. Laboratory Investigation. ,vol. 94, pp. 917- 926 ,(2014) , 10.1038/LABINVEST.2014.77

Sheela Rao, Lyndsey Welsh, David Cunningham, Robert H. te-Poele, Martin Benson, Andrew Norman, Claire Saffery, Ian Giddings, Paul Workman, Paul A. Clarke, Correlation of Overall Survival With Gene Expression Profiles in a Prospective Study of Resectable Esophageal Cancer Clinical Colorectal Cancer. ,vol. 10, pp. 48- 56 ,(2011) , 10.3816/CCC.2011.N.007

Soo Mi Kim, Yun-Yong Park, Eun Sung Park, Jae Yong Cho, Julie G. Izzo, Di Zhang, Sang-Bae Kim, Jeffrey H. Lee, Manoop S. Bhutani, Stephen G. Swisher, Xifeng Wu, Kevin R. Coombes, Dipen Maru, Kenneth K. Wang, Navtej S. Buttar, Jaffer A. Ajani, Ju-Seog Lee, Prognostic Biomarkers for Esophageal Adenocarcinoma Identified by Analysis of Tumor Transcriptome PLoS ONE. ,vol. 5, pp. e15074- ,(2010) , 10.1371/JOURNAL.PONE.0015074

Maria P. Alcolea, Philip Greulich, Agnieszka Wabik, Julia Frede, Benjamin D. Simons, Philip H. Jones, Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change Nature Cell Biology. ,vol. 16, pp. 615- 622 ,(2014) , 10.1038/NCB2963

Yue Chen, Tinghui Jiang, Aiwu Mao, Jianrong Xu, Esophageal cancer stem cells express PLGF to increase cancer invasion through MMP9 activation. Tumor Biology. ,vol. 35, pp. 12749- 12755 ,(2014) , 10.1007/S13277-014-2601-X

Yi-Bo Gao, Zhao-Li Chen, Jia-Gen Li, Xue-Da Hu, Xue-Jiao Shi, Zeng-Miao Sun, Fan Zhang, Zi-Ran Zhao, Zi-Tong Li, Zi-Yuan Liu, Yu-Da Zhao, Jian Sun, Cheng-Cheng Zhou, Ran Yao, Su-Ya Wang, Pan Wang, Nan Sun, Bai-Hua Zhang, Jing-Si Dong, Yue Yu, Mei Luo, Xiao-Li Feng, Su-Sheng Shi, Fang Zhou, Feng-Wei Tan, Bin Qiu, Ning Li, Kang Shao, Li-Jian Zhang, Lan-Jun Zhang, Qi Xue, Shu-Geng Gao, Jie He, Genetic landscape of esophageal squamous cell carcinoma Nature Genetics. ,vol. 46, pp. 1097- 1102 ,(2014) , 10.1038/NG.3076

Luigi Mari, Francesca Milano, Kaushal Parikh, Danielle Straub, Vincent Everts, Kees K. Hoeben, Paul Fockens, Navtej S. Buttar, Kausilia K. Krishnadath, A pSMAD/CDX2 complex is essential for the intestinalization of epithelial metaplasia. Cell Reports. ,vol. 7, pp. 1197- 1210 ,(2014) , 10.1016/J.CELREP.2014.03.074

Christopher J Peters, Jonathan RE Rees, Richard H Hardwick, James S Hardwick, Sarah L Vowler, Chin–Ann J Ong, Chunsheng Zhang, Vicki Save, Maria O'Donovan, Doris Rassl, Derek Alderson, Carlos Caldas, Rebecca C Fitzgerald, Oesophageal Cancer Clinical, Molecular Stratification OCCAMS Study Group, None, A 4-Gene Signature Predicts Survival of Patients With Resected Adenocarcinoma of the Esophagus, Junction, and Gastric Cardia Gastroenterology. ,vol. 139, pp. 1995- 2004 ,(2010) , 10.1053/J.GASTRO.2010.05.080

Marcus Bettstetter, Sabina Berezowska, Gisela Keller, Axel Walch, Annette Feuchtinger, Julia Slotta-Huspenina, Marcus Feith, Enken Drecoll, Heinz Höfler, Rupert Langer, Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome Human Pathology. ,vol. 44, pp. 829- 836 ,(2013) , 10.1016/J.HUMPATH.2012.08.005

Mitsuhiko Hanawa, Shioto Suzuki, Yoh Dobashi, Tetsu Yamane, Koji Kono, Nobuyuki Enomoto, Akishi Ooi, EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus. International Journal of Cancer. ,vol. 118, pp. 1173- 1180 ,(2006) , 10.1002/IJC.21454