Histochemical and immunocytochemical study of ubiquitinated neuronal inclusions in amyotrophic lateral sclerosis
作者： K. Mather , J. E. Martin , M. Swash , G. Vowles , A. Brown
DOI: 10.1111/J.1365-2990.1993.TB00419.X
关键词:
摘要: Ubiquinated cytoplasmic inclusions are a characteristic feature of the anterior horn cell pathology amyotrophic lateral sclerosis. The underlying abnormality leading to production these in this neurodegenerative motor system disease is unknown. Despite application wide range histochemical and immunocytochemical techniques we have been unable identify core constituent protein intraneuronal inclusions. A novel approach problem required.
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