Large Protein Absorptions from Small Changes on the Surface of Nanoparticles

作者: Morteza Mahmoudi , Vahid Serpooshan

DOI: 10.1021/JP2056255

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摘要: Due to their ultrasmall size, nanoparticles possess distinct properties, when compared with the bulk form of exact same material. These unique properties are now being exploited in biology and biomedicine order probe biological systems deliver biosensors or drugs into targeted areas. However, relatively little is known about interaction nanoscale objects living systems. In a fluid for example, various proteins associate nanoparticles. The small size high curvature angles bias physicochemical sizes, amounts presented on surface. differential display bound surface can influence tissue distribution, cellular uptake, effects This study aimed at verifying roughness nano-objects composition corresponding protein corona. A novel approach was used synthesize magnetic core–shell nanop...

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