Calcium Phosphates: A Survey of the Orthopaedic Literature

摘要: For over two decades, calcium phosphates have been the focus of many laboratory and clinical investigations (1–8). Particular interest has surrounded hydroxyapatite (HA), a naturally occurring phosphate present in tooth enamel vertebrate bone. In early 1980’s, dental community began using HA blocks coatings to augment bone encourage fixation restorative procedures ; chemical stability excellent biocompatibility made it an attractive material choice (1, 5, 9, 10). Subsequently, orthopaedic investigated for defect obliteration as implant coating, with encouraging results (3, 11, 12). More recently, attention given biphasic (BCP), which combine tricalcium (TCP) different ratios. Solid, porous, granular forms BCP materials employed filling defects (13–16). Current studies involving use block drug delivery system either cement or growth factors all show promise, do composite materials, such (17–19).