Indoleamine 2,3-dioxygenase in intestinal immunity and inflammation.
作者： Bobby J. Cherayil
DOI: 10.1002/IBD.20910
关键词:
摘要: Indoleamine 2,3-dioxygenase (IDO) is a tryptophan catabolizing enzyme that has number of immunoregulatory effects. It expressed at high levels in the gastrointestinal tract, particularly small intestine, and been implicated control intestinal inflammation. However, its precise role immunity not well understood. This review will summarize current state knowledge about IDO function, as it pertains to inflammatory responses gut.
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