Quality of life, sleep and rheumatoid arthritis (QUASAR): a protocol for a prospective UK mHealth study to investigate the relationship between sleep and quality of life in adults with rheumatoid arthritis.

摘要: Introduction People with rheumatoid arthritis (RA) frequently report reduced health-related quality of life (HRQoL), the impact one’s health has on physical, emotional and social well-being. There are likely numerous causes for poor HRQoL, but people RA have identified sleep disturbances as a key contributor to their This study will identify sleep/wake rhythm-associated parameters that predict HRQoL in patients RA. Methods analysis prospective cohort recruit 350 RA, aged 18 years or older. Following completion paper-based baseline questionnaire, participants record data 10 symptoms including pain, fatigue mood two times day 30 days using study-specific mobile application (app). A triaxial accelerometer continuously daytime activity estimate evening over days. Every following initiation, complete questionnaire measures disease specific (Arthritis Impact Measurement Scale 2-Short Form (AIMS2-SF)) generic (WHOQOL-BREF) life. final be completed at 60 after entering study. The primary outcomes AIMS2-SF WHOQOL-BREF. Structural equation modelling latent trajectory models used examine relationship between time. Ethics dissemination Results from this disseminated regional international conferences, peer-reviewed journals Patient Public Engagement events, appropriate.